This cross-sectional analysis using data from the ISA birth cohort examined the association between medical conditions, environmental exposures, and elevated levels of fractional exhaled nitric oxide (FeNO), a marker of airway inflammation. Rhinitis and wheezing were associated with elevated FeNO levels in both women and children. Environmental exposures such as waste burning, and para-occupational pesticide exposure were also associated with elevated FeNO levels in this agricultural population. These findings suggest that airway inflammation may be influenced by medical conditions and environmental exposures in rural communities.
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A cross-sectional analysis of medical conditions and environmental factors associated with fractional exhaled nitric oxide (FeNO) in women and children from the ISA birth cohort, Costa Rica. Werthman, D., van Wendel de Joode, B., Cuffney, M. T., Reich, B. J., Soto-Matinez, M. E., Corrales-Vargas, A., Palomo-Cordero, L. D., Peñaloza-Castañeda, J., Hoppin, J.A. 2023. Environmental Research. DOI: 10.1016/j.envres.2023.116449. PMID: 37356534. Spanish version (unofficial translation).