This study examined the effects of exposure to commonly used pesticides, lead, and manganese in pregnant women on thyroid hormone concentrations. Metabolites of pesticides in urine, concentrations of manganese in hair and blood, and lead in blood were analyzed. It was observed that women with higher levels of ETU and pyrimethanil metabolites had a decrease in FT4 hormone, while the presence of chlorpyrifos, pyrethroids, MnB, MnH, PbB showed effects similar to hyperthyroidism. Some effects were immediate (ETU, pyrimethanil, MnB), others delayed (chlorpyrifos, MnH, PbB), or both (pyrethroids), suggesting possible different mechanisms of action.
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